Our undergraduate researchers Ozlem Neyisci and Gulce Isil Gokce's project titled "Local and Targeted Drug Delivery Systems for the Treatment of Glioblastoma", supervised by Prof. Dr. Vasıf Hasırcı and Dr. Tugba Dursun-Usal, was awarded the Research Project Support Programme for Undergraduate Students/2209A grant by The Scientific and Technological Research Council of Turkey (TUBITAK) and also the Undergraduate Research Projects fund of AdımODTÜ, a program of the Middle East Technical University. We congratulate them and wish them continued success.

Ozlem Neyisci and Gulce Isil Gokce
METU Molecular Biology and Genetics (Senior Students)

Project Abstract:
This project aims to create a targeted and local drug delivery system based on improving the existing treatment routes and preventing the side effects of the most common treatments. For this purpose, a PLGA sponge loaded with PLGA nanoparticles is being used as the local delivery system. The nanoparticles encapsulate an anticancer drug, Temozolomide (TMZ), and will be tagged with nuclear localization signal (NLS) to target the nuclei of the tumor cells.