Selamet, H., Isik, S., Yucel, D., & Hasirci, V. (2026). Construction of a 3D printed, human gingival MSC seeded alveolar bone implant. Journal of Applied Biomaterials & Functional Materials, 24, 1-15.

DOI: https://doi.org/10.1177/22808000261452915

Key messages of the study: 

1. Tissue engineered, 3D printed PCL scaffolds functionalized with BMP2 and seeded with hGMSC cells showed enhanced osteogenic potential in vitro.

2. The 3D printing process allowed fabrication of scaffolds with controlled pore distribution and internal architecture ensuring optimal cell performance.

3. hGMSCs exhibited high differentiation capacity, confirming their suitability as an accessible and potent stem cell source for bone tissue engineering.