BİOMATENBİYOMALZEME VE DOKU MÜHENDİSLİĞİ MÜKEMMELİYET MERKEZİ


Son Yayınlar

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2017


  • Kayabolen, A., Keskin, D., Aykan, A., Karslıoglu, Y., Zor, F., Tezcaner, A. (2017). Native Extracellular Matrix/Fibroin Hydrogels for Adipose Tissue Engineering with Enhanced Vascularization. Biomedical Materials. DOI: 10.1088/1748-605X/aa6a63
  • Eke, G., Mangir, N., Hasirci, N., MacNeil, S., Hasirci, V. (2017). Development of a UV Crosslinked Biodegradable Hydrogel Containing Adipose Derived Stem Cells to Promote Vascularization for Skin Wounds and Tissue Engineering. Biomaterials 129, 188-198. DOI: 10.1016/j.biomaterials.2017.03.021
  • Gunay, B., Hasirci, N. & Hasirci, H. (2017). A Cell Attracting Composite of Lumbar Fusion Cage. Journal of Biomaterials Science, Polymer Edition, DOI: 10.1080/09205063.2017.1301771
  • Pazarceviren, E., Erdemli, O., Keskin, D., Tezcaner, A. (2017) Clinoptilolite/PCL-PEG-PCL composite scaffolds for bone tissue engineering applications. J Biomater Appl. doi: 10.1177/0885328216680152. Epub 2016 Nov 23. 
  • Durusu, I.Z., Husnugil, H.H., Atas, H., Biber, A., Gerekci, S., Gülec, E.A., Özen, C. (2017). Anti-cancer effect of clofazimine as a single agentand in combination with cisplatin on U266 multiple myeloma cell line. Leukemia Research, 55, 33-40. doi: 10.1016/j.leukres.2017.01.019


2016


  • Polat, G.G., Akgun, O.M., Simsek, B., Saracli, M.A., Heper, S. & Hasirci, V. (2016) Fluoride-containing Anti-caries pH-sensitive Release System and Its Effect on Streptococcus Mutants. Fluoride 49(4 Pt 1):458-466
  • Hasturk, O., Sivas, A., Karasozen, B., Demirci, U., Hasirci, N., & Hasirci, V. (2016). Quantification of type, timing, and extent of cell body and nucleus deformations caused by the dimensions and hydrophilicity of square prism micropillars. Advanced Healthcare Materials 5 (23), 2972-2982
  • Pekozer, GG., Kose, GT., Hasirci, V. (2016). Influence of co-culture on osteogenesis and angiogenesis of bone marrow mesenchymal stem cells and aortic endothelial cells. Microvascular Research 108, 1-9, 1
  • Dilek, C., Hasirci, N., Novendra, N. (2106). Supercritical Processing of CO2-philic Polyhedral Oligomeric Silsesquioxane (POSS)-poly(l-lactic acid) Composites, The Journal of Supercritical Fluids. (Science Citation Index). DOI:10.1016/j.supflu.2016.06.022.
  • Koklukaya, S.Z., Sezer, S., Aksoy, S., Hasirci, N. (2016). Polyacrylamide Based Semi-interpenetrating Networks for Entrapment of Laccase and Their Use in Azo Dye Decolorization. Biotechnology and Applied Biochemistry, Biotechnol Appl Biochem. 63, 5, 699–707, (Science Citation Index) DOI: 10.1002/bab.1417.
  • Ucar, S., Ermis, M., Hasirci, N.(2016) Modified Chitosan Scaffolds: Proliferative, Cytotoxic, Apoptotic and Necrotic Effects on Saos-2 Cells and Antimicrobial Effect on E.coli, Journal of Bioactive and Compatible Polymers. 31(3) 304–319. (Science Citation Index) DOI: 10.1177/0883911515627471
  • Kara, F.,  Aksoy, E.A.., Calamak, S., Hasirci,N., Aksoy, S. (2016). Immobilization of Heparin on Chitosan Grafted Polyurethane Films to Enhance Its Anti-adhesive and Antibacterial Properties Against Bacteria, Journal of Bioactive and Compatible Polymers. 31(1) 72- 90. DOI: htpp://dx.doi.org/10.1177/0883911515598794
  • Komez, A., Baran, ET., Erdem, U., Hasirci, N., & Hasirci, V. (2016). Construction of a patterned hydrogel—fibrous mat bilayer structure to mimic choroid and Bruch's membrane layers of retina. Journal of Biomedical Materials Research Part A 104 (9), 2166-2177
  • Ermis, M., Akkaynak, D., Chen, P., Demirci, U., Hasirci, V. (2016). A high throughput approach for analysis of cell nuclear deformability at single cell level. Scientific Reports 6
  • Hasirci, N., Kilic, C., Kömez, A., Bahcecioglu, G., Hasirci, V. (2016) Hydrogels in regenerative medicine. GELS HANDBOOK: Fundamentals, Properties and Applications Volume 2


2015


  • Eke, G., Goni-de-Cerio, F., Suarez-Merino, B., Hasirci, N., & Hasirci, V. (2015). Biocompatibility of Dead Sea Water and retinyl palmitate carrying poly(3-hydroxybutyrate-co-3-hydroxyvalerate) micro/nanoparticles designed for transdermal skin therapy. Journal of Bioactive and Compatible Polymers [PDF]

  • Kiziltay, A., Marcos-Fernandez, A., San Roman, J., Sousa, R. A., Reis, R. L., Hasirci, V., & Hasirci, N. (2013). Poly(ester-urethane) scaffolds: effect of structure on properties and osteogenic activity of stem cells. Journal of Tissue Engineering and Regenerative Medicine. [PDF]


2014


  • Bagherifam, S., Skjeldal, F. M., Griffiths, G., Mælandsmo, G. M., Engebråten, O., Nyström, B., Hasirci, V., Hasirci, N. (2014). pH-Responsive Nano Carriers for Doxorubicin Delivery. Pharmaceutical Research. doi:10.1007/s11095-014-1530-0 [PDF]
  • Demirci, N., & Tönük, E. (2014). Non-integer viscoelastic constitutive law to model soft biological tissues to in-vivo indentation. Acta of Bioengineering and Biomechanics, Vol. 16(nr 4). DOI: 10.5277/ABB-00005-2014-03 [PDF]
  • Endogan Tanir, T., Hasirci, V., & Hasirci, N. (2014). Preparation and characterization of Chitosan and PLGA-based scaffolds for tissue engineering applications. Polymer Composites,  doi:10.1002/pc.23100
  • Bagherifam, S., Griffiths, G. W., Mælandsmo, G. M., Nyström, B., Hasirci, V., & Hasirci, N. (2014). Poly(sebacic anhydride) nanocapsules as carriers: effects of preparation parameters on properties and release of doxorubicin. Journal of Microencapsulation, 1–9. doi:10.3109/02652048.2014.973073
  • Kara, F., Aksoy, E. A., Yuksekdag, Z., Hasirci, N., & Aksoy, S. (2014). Synthesis and surface modification of polyurethanes with chitosan for antibacterial properties. Carbohydrate Polymers, 112, 39–47. doi:10.1016/j.carbpol.2014.05.019
  • Sezer, U. A., Billur, D., Huri, G., Huri, P. Y., Aksoy, E. A., Terzioglu, H., Konukseven, E., Hasirci, V., Hasirci, N. (2014). In Vivo Performance of Poly(ε-caprolactone) Constructs Loaded with Gentamicin Releasing Composite Microspheres for Use in Bone Regeneration. Journal of Biomaterials and Tissue Engineering, 4(10), 786–795. doi:10.1166/jbt.2014.1238
  • Ozgen O.,Hasirci V., Hasirci N. (2014) Effects of oxygen nitrogen  and argon plasmas on PMMA surfaces, Journal of Biomaterials and Tissue Engineering, J. Biomater. Tissue Eng., 4(6), 479-487
  • Aydemir Sezer, U., Arslantunali, D., Aksoy, E. A., Hasirci, V., & Hasirci, N. (2014). Poly(ε-caprolactone) composite scaffolds loaded with gentamicin-containing β-tricalcium phosphate/gelatin microspheres for bone tissue engineering applications. Journal of Applied Polymer Science, 131(8), n/a–n/a. doi:10.1002/app.40110
  • Saygun, I., Bal, V., Kızıltay, A., Huri, P. Y., Avcu, F., Üstün, K., Hasirci V., Hasirci, N. (2014). Proliferation and Differentiation of Mesenchymal Stem Cells in Chitosan Scaffolds Loaded with Nanocapsules Containing Bone Morphogenetic Proteins-4, Platelet-Derived Growth Factor and Insulin-Like Growth Factor 1. Journal of Biomaterials and Tissue Engineering, 4(3), 181–188. doi:10.1166/jbt.2014.1153
  • Hasirci N. (2014), Polimer-İlaç ve Polimer-Protein Konjugatları, Ed: Ayla Zırh Gürsoy, Nanofarmasötikler ve Uygulamaları, Kontrollu Salım Sistemleri Derneği Yayını, ISBN:978-605-85318-0-2, No:3, 151-166
  • Endogan, T., Kiziltay, A., Kose, G. T., Comunoglu, N., Beyzadeoglu, T., & Hasirci, N. (2014). Acrylic bone cements: Effects of the poly(methyl methacrylate) powder size and chitosan addition on their properties. Journal of Applied Polymer Science, 131(3), doi:10.1002/app.39662
  • Güney, A., & Hasirci, N. (2014). Properties and phase segregation of crosslinked PCL-based polyurethanes. Journal of Applied Polymer Science, 131(1), doi:10.1002/app.39758
  • Pektaş, O., & Tönük, E. (2014). Mechanical design, analysis, and laboratory testing of a dental implant with axial flexibility similar to natural tooth with periodontal ligament. Proceedings of  the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine. doi:10.1177/0954411914557713 [PDF]
  • Arslantunali, D., Dursun, T., Yucel, D., Hasirci, N., Hasirci, V. (2014). Peripheral nerve conduits: Technology update. Medical Devices: Evidence and Research, 7, 405-242.[PDF]
  • Sayin, E., Baran, E.T., Hasirci, V. (2014). Protein-based materials in load-bearing tissue-engineering  applications. Regenerative Medicine, 9(5), 687–701. [PDF]
  • Kinikoglu, B., Damour, O., Hasirci, V. (2014). Tissue engineering of oral mucosa: a shared concept with skin. Journal of Artificial Organs. DOI: 10.1007/s10047-014-0798-5
  • Endogan-Tanir, T., Hasirci, V., Hasirci, N. (2014). Electrospinning of chitosan/poly (lactic acid-co-glycolic acid)/hydroxyapatite composite nanofibrous mats for tissue engineering applications. Polymer Bulletin. DOI:10.1007/s00289-014-1234-y.[PDF]

  • Karadas,O., Yucel, D., Kenar, H., Kose, G., Hasirci, V. (2014).  Collagen scaffolds with in situ-grown calcium phosphate for osteogenic differentiation of Wharton’s jelly and menstrual blood stem cells. Journal of Tissue Engineering And Regenerative Medicine, 8,534–545. [PDF]
  • Kilic, C., Girotti, A., Rodriguez-Cabello, J., C., Hasirci, V. (2014). A collagen-based corneal stroma substitute with micro-designed architecture. Biomaterial Science, 2, 318-329 [PDF]
  • N. E. Vrana, O. Erdemli, G. Francius, A. Fahs, M. Rabineau, C. Debry, A. Tezcaner,D. Keskin, P. Lavalle. (2014). Double entrapment of growth factors by nanoparticles loaded into polyelectrolyte multilayer film. Journal of Materials Chemistry B, 2, 999-1008. DOI: 10.1039/C3TB21304H

  • Erdemli O, Usanmaz A, Keskin D, Tezcaner A. (2014). Characteristics and release profiles of MPEG-PCL-MPEG microspheres containing immunoglobulin G. Colloids and Surfaces B: Biointerfaces, 117, 487–496. DOI:10.1016/j.colsurfb.2014.01.037

  • Tezcaner, A., Keskin, D., Özen, S., Atilla, B., Usanmaz, A., Kocaefe, Ç. (2014) Controlled Drug Delivery For Anti-TNF α, 2014, PCT Application, (WO/2014/046631)

  • Bahcecioglu, G., Buyuksungur, A., Kiziltay, A., Hasirci, N., Hasirci, V. (2014). Construction and in vitro testing of a multilayered, tissue-engineered meniscus. Journal of Bioactive and Compatible Polymers, 29(3), 235-253. 

  • Ozcelik H., Padeste C., Hasirci V. Systematically organized nanopillar arrays reveal differences in adhesion and alignment properties of BMSC and Saos-2 cells. (2014). Colloids and Surfaces B: Biointerfaces. DOI:10.1016/j.colsurfb.2014.03.019.
  • Halili A. N., Hasirci N., Hasirci V. (2014). A multilayer tissue engineered meniscus substitute. Journal of Material Science: Materials in Medicine, 25, 1195-1209.
  • Eke G., Kuzmina A., Goreva A., Shishatskaya E., Hasirci N., Hasirci V.  (2014)  In vitro and Transdermal Penetration of PHBV Micro/Nanoparticles. Journal of Nanomaterials Science: Materials in Medicine. DOI:10.1007/s10856-014-5169-5.


2013


  • Arslantunali, D., Budak, G., & Hasirci, V. (2014). Multiwalled CNT-pHEMA composite conduit for peripheral nerve repair. Journal of Biomedical Materials Research. Part A, 102(3), 828–41. doi:10.1002/jbm.a.34727
  • Huri, P. Y., Huri, G., Yasar, U., Ucar, Y., Dikmen, N., Hasirci, N., & Hasirci, V. (2013). A biomimetic growth factor delivery strategy for enhanced regeneration of iliac crest defects. Biomedical Materials (Bristol, England), 8(4), 045009. doi:10.1088/1748-6041/8/4/045009

  • Ucar, S., Yilgor, P., Hasirci, V., & Hasirci, N. (2013). Chitosan-based wet-spun scaffolds for bioactive agent delivery. Journal of Applied Polymer Science, 130(5), 3759–3769. doi:10.1002/app.39629

  • Yilgor, P., Yilmaz, G., Onal, M. B., Solmaz, I., Gundogdu, S., Keskil, S., Sousa, R.A., Reis, R.L., Hasirci N., Hasirci, V. (2013). An in vivo study on the effect of scaffold geometry and growth factor release on the healing of bone defects. Journal of Tissue Engineering and Regenerative Medicine, 7(9), 687–96. doi:10.1002/term.1456

  • Ozerkan, T., Aydemir Sezer, U., Deliloglu Gurhan, İ., Gulce İz, S., Hasirci, N. (2013). Semi-IPN chitosan/polyvinylpyrrolidone microspheres and films: sustained release and property optimisation. Journal of Microencapsulation, 30(8), 762–70. doi:10.3109/02652048.2013.788084

  • Bilgic, H., Demiriz, M.,Ozler, Tayfun I,  Dogan, N., Gumus, S., Kiziltay, A., Endogan, T., Hasirci N., Hasirci, V.  (2013) Effects of EGF Containing Gelatin Sponges as Wound Healing Scaffolds, J. Biomater. Tissue Eng., 3(2), 205-211.
  • Ndreu Halili, A., Hasirci, N., & Hasirci, V. (2013). A Mechanically Functional Collagen-Based Construct Designed as a Meniscus Substitute. Journal of Biomaterials and Tissue Engineering, 3(2), 173–184. doi:10.1166/jbt.2013.1078

  • Hasırcı, N., Biyoteknoloji Alanında Çin Modeli, Ed: Mahmut Kiper, Biyoteknoloji Sektörel İnovasyon Sistemi: Kavramlar Dünyadan Örnekler Türkiye’de Durum ve Çıkarımlar, TTGV Yayınları, 77-96, March, 2013
  • Ozgen, O., Aksoy, E. A., Hasirci, V., & Hasirci, N. (2013). Surface characterization and radical decay studies of oxygen plasma-treated PMMA films. Surface and Interface Analysis, 45(4), 844–853. doi:10.1002/sia.5181

  • Aydemir Sezer, U., Ayse Aksoy, E., Hasirci, V., & Hasirci, N. (2013). Poly(ε-caprolactone) Composites Containing Gentamicin-Loaded β-Tricalcium Phosphate/Gelatin Microspheres as Bone Tissue Supports. Journal of Applied Polymer Science, 127(3), 2132–2139.


2012


  • Ozgen, O., Aksoy, A., Hasirci, H., Hasirci N. 2012, "Surface characterization and radical decay studies of oxygen plasma-treated PMMA films", Journal of Surface and Interface Analysis, DOI: 10.1002/sia.5181. [PDF]
  • Karadas, O., Yucel D., Kenar, H., Kose, G., Hasirci, V. 2012, "Collagen scaffolds with in situ-grown calcium phosphate for osteogenic differentiation of Wharton’s jelly and menstrual blood stem cells", Journal of Tissue Engineering and Regenerative Medicine, DOI: 10.1002/term.1555.
  • Küçükturhan, A., Hasırcı, V. (2012)Ürolojide nanoteknoloji uygulamaları, Moleküler Üroloji, Eds. L. Turkeri, A. Ozer, F. Narter, Publisher Uronkoloji Dernegi, Istanbul (Turkey), pp.711-720, ISBN 978-975-01697-2-4 
  • Ermis M., Bahcecioglu, G., Kandemir, B., Hasirci V., (2012) Kök hücreler, rejeneratif üroloji, ve doku mühendisliği, in Moleküler Üroloji, Eds. L. Turkeri, A. Ozer, F. Narter, Publisher Uronkoloji Dernegi, Istanbul (Turkey), pp. 721-748, 012, ISBN 978-975-01697-2-4 

  • Hasirci, V. & Pepe-Mooney, B.J. 2012, "Understanding the cell behavior on nano-/micro-patterned surfaces", Nanomedicine (London, England), DOI 10.2217/NNM.12.7 [PDF] 
  • Fedel, M., Endogan, T., Hasirci, N., Maniglio, D., Morelli, A., Chiellini, F., & Motta, A. 2012, "Blood compatibility of polymers derived from natural materials", Journal of Bioactive and Compatible Polymers, DOI 10.1177/0883911512446060 [PDF] 
  • Luca, A., Cilek, B., Hasirci, V., Sahin, S., & Sumnu, G. 2012 "Effect of degritting of phenolic extract from sour cherry pomace on encapsulation Efficiency—Production of Nano-suspension", Food Bioprocess Technol, DOI 10.1007/s11947-012-0880-z [PDF]
  • Sezer, U.A., Aksoy, E.A., Hasirci, V. & Hasirci, N. 2012, "Poly(ε-caprolactone) composites containing gentamicin-loaded  β -tricalcium phosphate/gelatin microspheres as bone tissue supports", Journal of Applied Polymer Science, DOI: 10.1002/app.37770. [PDF]
  • Yilgor, P., Yilmaz, G., Onal, M.B., Solmaz, I., Gundogdu, S., Keskil, S., Sousa, R.A., Reis, R.L., Hasirci, N. & Hasirci, V. 2012, "An in vivo study on the effect of scaffold geometry and growth factor release on the healing of bone defects", Journal of tissue engineering and regenerative medicine, DOI: 10.1002/1456. [PDF]
  • Kinikoglu, B., Rovere, M.R., Haftek, M., Hasirci, V. & Damour, O. 2012, "Influence of the mesenchymal cell source on oral epithelial development", Journal of Tissue Engineering and Regenerative Medicine, vol. 6, no. 3, pp. 245-252 [PDF].
  • Isikli, C., Hasirci, V. & Hasirci, N. 2012, "Development of porous chitosan/gelatin/hydroxyapatite composite scaffolds for hard tissue-engineering applications", Journal of Tissue Engineering and Regenerative Medicine, vol. 6, no. 2, pp. 135-143 [PDF]

  

2011


  • Demirbag, B., Kardesler, S., Buyuksungur, A., Kucukturhan, A., Eke, G., Hasirci, N., & Hasirci, V. (2012) Nanotechnology in Biomaterials: Nanoparticulates as Drug Delivery Systems, in Bionanotechnology II: Global Prospects, ed D. Reisner, Chapter 11, 227-246, 2011, CRC Press/Taylor and Francis, ISBN No: 143980463X, 9781439804636 [PDF]
  • Yucel, D., Kenar, H., Ndreu, A., Endogan, T., Hasirci, N., & Hasirci, V. (2012). Nanotechnology in Biomaterials: Nanofibers in Tissue Engineering. Biotechnology Global Prospects II. CRC Press Taaylor and Francis Group, 227-246. [PDF]
  • Demirbag, B., Huri, P.Y., Kose, G.T., Buyuksungur, A. & Hasirci, V. 2011, "Advanced cell therapies with and without scaffolds", Biotechnology Journal, vol. 6, no. 12, pp. 1437-1453 [PDF]
  • Kinikoglu, B., Rodriguez-Cabello, J.C., Damour, O. & Hasirci, V. 2011a, "A smart bilayer scaffold of elastin-like recombinamer and collagen for soft tissue engineering", Journal of materials science, Materials in medicine, vol. 22, no. 6, pp. 1541-1554 [PDF]
  • Kinikoglu, B., Rodríguez-Cabello, J.C., Damour, O. & Hasirci, V. 2011b, "The influence of elastin-like recombinant polymer on the self-renewing potential of a 3D tissue equivalent derived from human lamina propria fibroblasts and oral epithelial cells", Biomaterials, vol. 32, no. 25, pp. 5756-5764 [PDF]
  • Kenar, H., Kose, G.T., Toner, M., Kaplan, D.L. & Hasirci, V. 2011, "A 3D aligned microfibrous myocardial tissue construct cultured under transient perfusion", Biomaterials, vol. 32, no. 23, pp. 5320-5329 [PDF].
  • Aydin, E., Planell, J. & Hasirci, V. 2011, "Hydroxyapatite nanorod-reinforced biodegradable poly(l-lactic acid) composites for bone plate applications",  Journal of materials science, Materials in medicine, vol.22, pp. 2413–2427, Springer Netherlands [PDF]
  • Carletti, E., Endogan, T., Hasirci, N., Hasirci, V., Maniglio, D., Motta, A. & Migliaresi, C. 2011, "Microfabrication of PDLLA scaffolds", Journal of Tissue Engineering and Regenerative Medicine, vol. 5, no. 7, pp. 569-577 [PDF]
  • Padeste, C., Özçelik, H., Ziegler, J., Schleunitz, A., Bednarzik, M., Yücel, D. & Hasırcı, V. 2011, "Replication of high aspect ratio pillar array structures in biocompatible polymers for tissue engineering applications", Microelectronic Engineering, vol. 88, no. 8, pp. 1836-1839 [PDF]
  • Hasirci, V., Yilgor, P., Endogan, T., Eke, G., Hasirci, N., 2011 " Polymer Fundamentals: Polymer Synthesis", Comprehensive Biomaterials, vol. 1, pp. 349-371 [PDF]